Interstate 95 enters South Carolina on its 198-mile trek near the town of Hamer, South Carolina. It then travels south through Florence, South Carolina, where it meets up with Interstate 20 just west of the town. This stretch of I-95 is so heavily traveled that in 2004, the South Carolina Department of Transportation completed a ten mile long widening project. Heading south, I-95 crosses Lake Marion. After its 2 mile water crossing, Interstate 85 ends up in the city of Santee and then Harleysville where it has an interchange with Interstate 26.
At 1,927 miles, Interstate 95 is the longest north-south Interstate highway. I-95 is known for being the most heavily traveled Interstate. I-95 passes through more states than any other interstate in the United States highway system.
The southern terminus for this interstate is in the city of Miami, Florida, at a junction with U.S. Highway 1 and Alligator Alley. To the north the terminus is at the Canadian border at Houlton, Maine, where it becomes New Brunswick Route 95.